Cingulate Cortex

Acetaminophen Reduces Social Pain - Behavioral and Neural Evidence (Abstract)
* "Pain, whether caused by physical injury or social rejection, is an inevitable part of life. These two types of pain—physical and social—may rely on some of the same behavioral and neural mechanisms that register pain-related affect. To the extent that these pain processes overlap, acetaminophen, a physical pain suppressant that acts through central (rather than peripheral) neural mechanisms, may also reduce behavioral and neural responses to social rejection. In two experiments, participants took acetaminophen or placebo daily for 3 weeks. Doses of acetaminophen reduced reports of social pain on a daily basis (Experiment 1). We used functional magnetic resonance imaging to measure participants’ brain activity (Experiment 2), and found that acetaminophen reduced neural responses to social rejection in brain regions previously associated with distress caused by social pain and the affective component of physical pain (dorsal anterior cingulate cortex, anterior insula). Thus, acetaminophen reduces behavioral and neural responses associated with the pain of social rejection, demonstrating substantial overlap between social and physical pain." [Abstract]
* "C. Nathan DeWall, Geoff MacDonald, Gregory D. Webster, Carrie L. Masten, Roy F. Baumeister, Caitlin Powell, David Combs, David R. Schurtz, Tyler F. Stillman, Dianne M. Tice,Naomi I. Eisenberger."
* "Psychological Science Published online before print June 14, 2010, doi:10.1177/0956797610374741"

Posted by ALCHEssMIST - Alchemipedia - Cetacographer - Nirvana alliance.

Anterior Insula

Acetaminophen Reduces Social Pain - Behavioral and Neural Evidence (Abstract)
* "Pain, whether caused by physical injury or social rejection, is an inevitable part of life. These two types of pain—physical and social—may rely on some of the same behavioral and neural mechanisms that register pain-related affect. To the extent that these pain processes overlap, acetaminophen, a physical pain suppressant that acts through central (rather than peripheral) neural mechanisms, may also reduce behavioral and neural responses to social rejection. In two experiments, participants took acetaminophen or placebo daily for 3 weeks. Doses of acetaminophen reduced reports of social pain on a daily basis (Experiment 1). We used functional magnetic resonance imaging to measure participants’ brain activity (Experiment 2), and found that acetaminophen reduced neural responses to social rejection in brain regions previously associated with distress caused by social pain and the affective component of physical pain (dorsal anterior cingulate cortex, anterior insula). Thus, acetaminophen reduces behavioral and neural responses associated with the pain of social rejection, demonstrating substantial overlap between social and physical pain." [Abstract]
* "C. Nathan DeWall, Geoff MacDonald, Gregory D. Webster, Carrie L. Masten, Roy F. Baumeister, Caitlin Powell, David Combs, David R. Schurtz, Tyler F. Stillman, Dianne M. Tice,Naomi I. Eisenberger."
* "Psychological Science Published online before print June 14, 2010, doi:10.1177/0956797610374741"

Social Rejection

Acetaminophen Reduces Social Pain - Behavioral and Neural Evidence (Abstract)
* "Pain, whether caused by physical injury or social rejection, is an inevitable part of life. These two types of pain—physical and social—may rely on some of the same behavioral and neural mechanisms that register pain-related affect. To the extent that these pain processes overlap, acetaminophen, a physical pain suppressant that acts through central (rather than peripheral) neural mechanisms, may also reduce behavioral and neural responses to social rejection. In two experiments, participants took acetaminophen or placebo daily for 3 weeks. Doses of acetaminophen reduced reports of social pain on a daily basis (Experiment 1). We used functional magnetic resonance imaging to measure participants’ brain activity (Experiment 2), and found that acetaminophen reduced neural responses to social rejection in brain regions previously associated with distress caused by social pain and the affective component of physical pain (dorsal anterior cingulate cortex, anterior insula). Thus, acetaminophen reduces behavioral and neural responses associated with the pain of social rejection, demonstrating substantial overlap between social and physical pain." [Abstract]
* "C. Nathan DeWall, Geoff MacDonald, Gregory D. Webster, Carrie L. Masten, Roy F. Baumeister, Caitlin Powell, David Combs, David R. Schurtz, Tyler F. Stillman, Dianne M. Tice,Naomi I. Eisenberger."
* "Psychological Science Published online before print June 14, 2010, doi:10.1177/0956797610374741"

Pain

Acetaminophen Reduces Social Pain - Behavioral and Neural Evidence (Abstract)
* "Pain, whether caused by physical injury or social rejection, is an inevitable part of life. These two types of pain—physical and social—may rely on some of the same behavioral and neural mechanisms that register pain-related affect. To the extent that these pain processes overlap, acetaminophen, a physical pain suppressant that acts through central (rather than peripheral) neural mechanisms, may also reduce behavioral and neural responses to social rejection. In two experiments, participants took acetaminophen or placebo daily for 3 weeks. Doses of acetaminophen reduced reports of social pain on a daily basis (Experiment 1). We used functional magnetic resonance imaging to measure participants’ brain activity (Experiment 2), and found that acetaminophen reduced neural responses to social rejection in brain regions previously associated with distress caused by social pain and the affective component of physical pain (dorsal anterior cingulate cortex, anterior insula). Thus, acetaminophen reduces behavioral and neural responses associated with the pain of social rejection, demonstrating substantial overlap between social and physical pain." [Abstract]
* "C. Nathan DeWall, Geoff MacDonald, Gregory D. Webster, Carrie L. Masten, Roy F. Baumeister, Caitlin Powell, David Combs, David R. Schurtz, Tyler F. Stillman, Dianne M. Tice,Naomi I. Eisenberger."
* "Psychological Science Published online before print June 14, 2010, doi:10.1177/0956797610374741"

Social Pain

Acetaminophen Reduces Social Pain - Behavioral and Neural Evidence (Abstract)
* "Pain, whether caused by physical injury or social rejection, is an inevitable part of life. These two types of pain—physical and social—may rely on some of the same behavioral and neural mechanisms that register pain-related affect. To the extent that these pain processes overlap, acetaminophen, a physical pain suppressant that acts through central (rather than peripheral) neural mechanisms, may also reduce behavioral and neural responses to social rejection. In two experiments, participants took acetaminophen or placebo daily for 3 weeks. Doses of acetaminophen reduced reports of social pain on a daily basis (Experiment 1). We used functional magnetic resonance imaging to measure participants’ brain activity (Experiment 2), and found that acetaminophen reduced neural responses to social rejection in brain regions previously associated with distress caused by social pain and the affective component of physical pain (dorsal anterior cingulate cortex, anterior insula). Thus, acetaminophen reduces behavioral and neural responses associated with the pain of social rejection, demonstrating substantial overlap between social and physical pain." [Abstract]
* "C. Nathan DeWall, Geoff MacDonald, Gregory D. Webster, Carrie L. Masten, Roy F. Baumeister, Caitlin Powell, David Combs, David R. Schurtz, Tyler F. Stillman, Dianne M. Tice,Naomi I. Eisenberger."
* "Psychological Science Published online before print June 14, 2010, doi:10.1177/0956797610374741"

Paracetamol

Acetaminophen Reduces Social Pain - Behavioral and Neural Evidence (Abstract)
* "Pain, whether caused by physical injury or social rejection, is an inevitable part of life. These two types of pain—physical and social—may rely on some of the same behavioral and neural mechanisms that register pain-related affect. To the extent that these pain processes overlap, acetaminophen, a physical pain suppressant that acts through central (rather than peripheral) neural mechanisms, may also reduce behavioral and neural responses to social rejection. In two experiments, participants took acetaminophen or placebo daily for 3 weeks. Doses of acetaminophen reduced reports of social pain on a daily basis (Experiment 1). We used functional magnetic resonance imaging to measure participants’ brain activity (Experiment 2), and found that acetaminophen reduced neural responses to social rejection in brain regions previously associated with distress caused by social pain and the affective component of physical pain (dorsal anterior cingulate cortex, anterior insula). Thus, acetaminophen reduces behavioral and neural responses associated with the pain of social rejection, demonstrating substantial overlap between social and physical pain." [Abstract]
* "C. Nathan DeWall, Geoff MacDonald, Gregory D. Webster, Carrie L. Masten, Roy F. Baumeister, Caitlin Powell, David Combs, David R. Schurtz, Tyler F. Stillman, Dianne M. Tice,Naomi I. Eisenberger."
* "Psychological Science Published online before print June 14, 2010, doi:10.1177/0956797610374741"

Acetaminophen

Acetaminophen Reduces Social Pain - Behavioral and Neural Evidence (Abstract)
* "Pain, whether caused by physical injury or social rejection, is an inevitable part of life. These two types of pain—physical and social—may rely on some of the same behavioral and neural mechanisms that register pain-related affect. To the extent that these pain processes overlap, acetaminophen, a physical pain suppressant that acts through central (rather than peripheral) neural mechanisms, may also reduce behavioral and neural responses to social rejection. In two experiments, participants took acetaminophen or placebo daily for 3 weeks. Doses of acetaminophen reduced reports of social pain on a daily basis (Experiment 1). We used functional magnetic resonance imaging to measure participants’ brain activity (Experiment 2), and found that acetaminophen reduced neural responses to social rejection in brain regions previously associated with distress caused by social pain and the affective component of physical pain (dorsal anterior cingulate cortex, anterior insula). Thus, acetaminophen reduces behavioral and neural responses associated with the pain of social rejection, demonstrating substantial overlap between social and physical pain." [Abstract]
* "C. Nathan DeWall, Geoff MacDonald, Gregory D. Webster, Carrie L. Masten, Roy F. Baumeister, Caitlin Powell, David Combs, David R. Schurtz, Tyler F. Stillman, Dianne M. Tice,Naomi I. Eisenberger."
* "Psychological Science Published online before print June 14, 2010, doi:10.1177/0956797610374741"

Performance

With This Rinse, Performance Improves (New York Times, July 19, 2010)
* "Exercise scientists say they have stumbled on an amazing discovery. Athletes can improve their performance in intense bouts of exercise, lasting an hour or so, if they merely rinse their mouths with a carbohydrate solution. They don’t even have to swallow it."
* "It has to be real carbohydrates, though; the scientists used a solution of water and a flavorless starch derivative called maltodextrin. Artificial sweeteners have no effect."
* "And the scientists think they have figured out why it works. It appears that the brain can sense carbohydrates in the mouth, even tasteless ones. The sensors are different from the ones for sweetness, and they prompt the brain to respond, spurring on the athlete."

Mood

Pulse of the Nation: U.S. Mood Throughout the Day inferred from Twitter (Poster)
* This poster attempts to gauge the mood throughout the day of America's 7% Twitter Users.

Pulse of the Nation: U.S. Mood Throughout the Day inferred from Twitter (Youtube Video)

Cognitive Decline

Handgrip strength and cognitive decline in older Mexican Americans. [PubMed Abstract]
* "CONCLUSION: Older Mexican Americans with reduced handgrip strength at baseline demonstrated a statistically significant decline in cognitive function over a 7-year period. By contrast, participants in the highest handgrip strength quartile maintained a higher level of cognitive function."
* Alfaro-Acha A, Al Snih S, Raji MA, Kuo YF, Markides KS, Ottenbacher KJ.
* J Gerontol A Biol Sci Med Sci. 2006 Aug;61(8):859-65.

Handgrip Strength

Handgrip strength and mortality in the oldest old population: the Leiden 85-plus study
* "Handgrip strength, a surrogate measurement of overall muscular strength, is a predictor of all-cause mortality in the oldest old population and may serve as a convenient tool for prognostication of mortality risk among elderly people."
* Carolina H.Y. Ling, MD, Diana Taekema, MD, Anton J.M. de Craen, PhD, Jacobijn Gussekloo, MD PhD, Rudi G.J. Westendorp, MD PhD and Andrea B. Maier, MD PhD
* CMAJ • March 23, 2010; 182 (5). First published February 8, 2010; doi:10.1503/cmaj.091278

Handgrip strength and cognitive decline in older Mexican Americans. [PubMed Abstract]
* "CONCLUSION: Older Mexican Americans with reduced handgrip strength at baseline demonstrated a statistically significant decline in cognitive function over a 7-year period. By contrast, participants in the highest handgrip strength quartile maintained a higher level of cognitive function."
* Alfaro-Acha A, Al Snih S, Raji MA, Kuo YF, Markides KS, Ottenbacher KJ.
* J Gerontol A Biol Sci Med Sci. 2006 Aug;61(8):859-65.

Anosmia

Homeopathic treatment works! (But not in a good way.) - July 19, 2010 (Nature Blog)
* "Terence Davidson and Wendy Smith, of the University of California, San Diego, looked at a set of nine criteria* for establishing a causal relationship and concluded that zinc nasal therapy can cause smell loss (anosmia). Their paper also details 25 patients who turned up at their Nasal Dysfunction Clinic complaining of smell loss after use of homeopathic zinc gel – which, unusually for a homeopathic treatment, does have an active ingredient."

Zinc Gluconate

Homeopathic treatment works! (But not in a good way.) - July 19, 2010 (Nature Blog)
* "Concerns that popular ‘homeopathic’ cold remedy zinc gluconate can cause a loss of smell have been around for a while. Now an analysis by two San Diego researchers shows these concerns may be well founded."

Homeopathic Treatment

Homeopathic treatment works! (But not in a good way.) - July 19, 2010 (Nature Blog)
* "Concerns that popular ‘homeopathic’ cold remedy zinc gluconate can cause a loss of smell have been around for a while. Now an analysis by two San Diego researchers shows these concerns may be well founded."

Mayer-Rokitansky-Küster-Hauser Syndrome

Oral Sex, a Knife Fight and Then Sperm Still Impregnated Girl (ABC News)
* "In 1988, a 15-year-old girl living in the small southern African nation of Lesotho came to local doctors with all the symptoms of a woman in labor. But the doctors were quickly puzzled because, upon examination, she didn't have a vagina."

Mullerian Agenesis

Oral Sex, a Knife Fight and Then Sperm Still Impregnated Girl (ABC News)
* "In 1988, a 15-year-old girl living in the small southern African nation of Lesotho came to local doctors with all the symptoms of a woman in labor. But the doctors were quickly puzzled because, upon examination, she didn't have a vagina."

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